Concurrent presentation of erythrodermic lichen planus and squamous cell carcinoma: Coincidence or malignant transformation?

Concurrent presentation of erythrodermic lichen planus and squamous cell carcinoma: Coincidence or malignant transformation?

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Lichen planus is a common papulosquamous disorder affecting about 1-2% of the population, neoplastic transformation of cutaneous lichen planus lesions occurs very rarely.A 40 year old female patient presented with a 1 year history of developing multiple, itchy, pigmented lesions over both lower legs which gradually spread to involve the whole body.A few tense bullae BCAA XDM SPIKED POWDER BERRIES were seen on the extremities.An erythematous fleshy lesion was seen on the upper aspect of the left buttock.Skin biopsy from a plaque on the right forearm showed features suggestive of lichen planus.

Skin biopsy of a bullae showed a sub epidermal bulla filled with a mixed inflammatory infiltrate.Direct immunofluorescence revealed no immunoreactants along the basement membrane zone.A diagnosis of erythrodermic lichen planus with bullous lichen planus was made.Biopsy of fleshy lesion of left buttock revealed a moderately differentiated squamous cell Collections carcinoma.Erythrodermic lichen planus with bullous lesions and secondary squamous cell carcinoma; these occurences in a single patient is extremely rare and has not been previously reported to the best of our knowledge.